Scott Johnston is joined by Doctor Jesse Charles, M.D. Jesse is a rural medical doctor and longtime adherent to the Uphill Athlete training methods. As a general practitioner in a rural setting, Jesse sees a wide variety of patients, from those at peak health, to the infirm. In this episode, Scott and Jesse discuss changes that take place as the result of regular exercise; exercise as a ‘phase change’ in the functioning of the body; how exercise facilitates learning; responses of the heart to exercise; nervous system changes and loss of motor units through time; the importance of balance practices in aging populations; the evolution of mitochondria; gut bacteria as a health indicator throughout life; dietary considerations for gut health; training progressions and adaptations for increasing vitality; and thoughts on arthritis prevention.
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References:
- Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate
- Molecular Choreography of Acute Exercise
- Hyperglycaemia is associated with impaired muscle signalling and aerobic adaptation to exercise
- Physical activity offsets genetic risk for incident depression assessed via electronic health records in a biobank cohort study
- MAP training: combining meditation and aerobic exercise reduces depression and rumination while enhancing synchronized brain activity
- Exercise Alters Gut Microbiota Composition and Function in Lean and Obese Humans
- Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism
- Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain
- Studies of a targeted risk reduction intervention through defined exercise (STRRIDE)
- BDNF polymorphism predicts the rate of decline in skilled task performance and hippocampal volume in healthy individuals
- Is Your Blood Sugar Undermining Your Workouts?
- Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health
- Association Between Dietary Fiber and Lower Risk of All-Cause Mortality: A Meta-Analysis of Cohort Studies.